Developing an optimal substance testing strategy

During the development of an optimal substance testing strategy, the cost of the necessary laboratory tests are being minimized with the help of literature data research and with the use of QSAR or cross-reading methods, in accordance with REACH requirements and cost-efficiency aspects.

Laboratory background

An internationally well-acknowledged research laboratory having all the necessary qualifications which are required to be REACH compatible. The highly qualified staff is ready to answer your questions and help you in any issues.

Our partner has GLP and ISO qualifications and meets the international directives (ICH, OECD, OPPTS, US EPA etc).

Services:

Determination of physical and chemical properties required for the submission of REACH registration dossier

  • Appearance/physical status/colour
  • Melting point/Freezing point
  • Boiling point
  • Density
  • Granulometry
  • Vapour pressure
  • Partition coefficient
  • Water solubility
  • Surface tension
  • Flash point
  • Self-ignition temperature
  • Flammability
  • Explosivity
  • Oxidising properties
  • Stability in organic solvents and identity in relevant degradation products
  • Dissociation constant
  • Viscosity
  • Hydrolisis
  • Biodegradation in water
  • Biodegradation in water and sediment simulation tests
  • Biodegradation in soil
  • Adsorption/desorption
Determination of toxicology properties required for the submission of REACH registration dossier
  • Basic toxicokinetics
  • Acute toxicity: oral
  • Acute toxicity: inhalation
  • Acute toxicity: dermal
  • Skin irritation/corrosion
  • Eye irritation
  • Skin sensitisation
  • Repeated dose toxicity: oral
  • Repeated dose toxicity: dermal
  • Repeated dose toxicity: inhalation
  • Genetic toxicity
  • Reproductive toxicity
  • Development toxicity/teratogenicity
Determination of ecotoxicology properties required for the submission of REACH registration dossier
  • Short term toxicity testing on fish
  • Long term toxicity testing on fish
  • Short term toxicity testing on invertebrates
  • Long term toxicity testing on invertebrates
  • Toxicity testing on aquatic algaes and blue algaes
  • Toxicity testing on microorganisms
  • Soil toxicity
  • Toxicity testing on soil macroorganisms (except arthropods)
  • Toxicity testing on terrestrial arthropods
  • Toxicity testing on terrestrial plants
  • Toxicity testing on soil microorganisms
  • Toxicity testing on birds
REACH 2009: REACH implementation, consultancy, registration

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